業績PUBLICATIONS
Publication List
Original paper
2018
77) "薬学部生のキャリアに対する意識調査ー女子学生が考えるキャリアとはー," 前田 徹、平松佑彩、佐伯憲一、水谷秀樹、吉川昌江、青柳 裕、矢野玲子、高橋誠弥、原崎周平、日野知証 薬学教育 2018 , 2 2018-028.
76) "Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O,20O-diacetyl kamebakaurin in mice," Yoshioka, H.; Ohnishi, H.; Yoshikawa, M.; Gui, M.-Y.; Jin, Y.-R.; Li, X.-W.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Aoyagi, Y. Fundamental Toxicol. Sci. 2018, 5, 161-165..
75) "1O,20O-diacetyl kamebakaurin protects against acetaminophen-induced hepatotoxicity in mice," Yoshioka, H.; Nonogaki, T.; Ohnishi, H.; Fukuishi, N.; Yoshikawa, M; Gui, M.-Y.; Jin, X.-R.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Aoyagi, Y. Biomed. Res. 2018, 39, 251-260.
74) "Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice," Yoshioka, H.; Mizuno, Y.; Ymamaguchi, T.; Ichimaru, Y.; Takeya, K.; Hitotsuyanagi, Y.; Nonogakl, T. Biomedicine & Pharmacotherapy 2018, 99, 214-219.
2017
73) "Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibiting lipid peroxidation and inflammatory response in mice”, Yoshioka, H.; Aoyagi, Y.; Fukuiishi, N.; Gui, M.-Y.; Jin, Y. R.; Li, X.-W.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Nonogaki, T. Pharmacol. Rep. 2017, 69, 903-907.
2016
72) 図書館有効利用の一事例-金城学院大学薬学部における屋根瓦方式PBLチュートリアル教育ー,” 青柳 裕、矢野玲子、（故）安藤裕明、田中宏樹、今井和佳子、吉岡亜佳音、石田翔子、西尾十和子、今井幹典、（故）林 弥生、安田公夫、千葉 拓、日野知証 薬学図書館 2016, 61, 99-107.
2014
71) "Efficient transformation of 7,14-dihydroxy-ent-kaurenes to novel ent-abietanes having cis-fused alfa-methylene gamma-lactones under Mitsunobu reaction conditions and their cytotoxicities," Aoyagi, Y.; Ozawa, K.; Hasuda, T.; Gui, M.-Y.; Jin, Y.-R.; Li, X.-W.; Fukaya, H.; Yano, R.; Hitotsuyanagi, Y.; Takeya. K. Tetrahedron 2014, 70, 3030-3041.
70) "Semisynthesis of salvianculin E analogues and their antitrypanosomal activity," Aoyagi, Y.; Fujiwara, K.; Yamazaki, A.; Sugawara, N.; Yano, R.; Fukaya, H.; Hitotsuyanagi, Y.; Takeya, K.; Ishiyama, A.; Iwatsuki, M.; Otoguro, K.; Yamada, H.; Omura, S. Bioorg. Med. Chem. Lett. 2014, 24, 442-446.
2013
69) "Conformational folding of mycobacterial methoxy- and ketomycolic acids facilitated by alfa-methyl trans-cyclopropane groups rather than cis-cyclopropane units," Villeneuve, M.; Kawai, M.; Horiuchi, K.; Watanabe, M.; Aoyagi, Y.; Hitsotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnikin, D. E. Microbiology 2013, 159, 2405-2415.
68) "Absolute structures of stemona-lactam S and tuberostemospiroline, alkaloids from Stemona tuberosa," Fukaya, H; Hitotsuyanagi, Y.; Aoyagi, Y.; Shu, Z.; Komatsu, K.; Takeya, K. Chem. Pharm. Bull. 2013, 61, 1085-1089.
67) "Abietane diterpenoids and a seaquiterpene pyridine alkaloid from Euonymus lutchuensis," Inaba, Y.; Hasuda, T.; Hitotsuyanagi, Y.; Aoyagi, Y.; Fujikawa, N.; Onozaki, A.; Watanabe, A.; Kinoshita, T.; Takeya, K. J. Nat. Prod. 2013, 76, 1085-1090.
2011
66) “Semisynthesis of triptolide analogues part III ~ Effect of furan ring on cytotoxic activities,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Fukaya, H.; Takeya, K.;
65) “Salvilucalin C, a novel rearranged neoclerodane diterpene from Salvia leucantha,”
64) “Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-kappaB activation,” Aoyagi, Y.; Adachi, Y.; Ozawa, K.; Yokomizo, C.; Gui, M.-G.; Jin, Y.-R.; Li, Y.-R.; Ohno, N.; Takeya, K. Bioorg. Med. Chem. 2011, 19, 2450-2457.
2010
63) “Differential conformational behaviors of alfa-mycolic acids in Langmuir monolayers and computer simulations,” Villeneuve, M.; Kawai, M.; Watanabe, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnikin, D. E.; Nakahara, H. Chem. Phys. Lipids 2010, 163, 569-579.
2009
62) “First asymmetric synthesis of CJ-14877 and its enantiomer and their interleukin-1beta inhibitorty activities,” Aoyagi, Y.; Adachi, Y.; Akagi, S.; Ohno, N.; Takeya, K. Bioorg. Med. Chem. Lett. 2009, 19, 1876-1878.
61) “Cytotoxic bisnor-and norditerpene dilactones having 7alfa, 8alfa-epoxy-9,11-enolide substructure from Podocarpus macrophyllus D. Don,” Sato, K.; Inaba, Y.; Park, H. –S.; Akiyama, T.; Koyama, T.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Chem. Pharm. Bull. 2009, 57, 668-679.
60) “New cytotoxic nor- and bisnorditerpene dilactones, makilactones A-D, from Podocarpus macrophyllus D. DON,” Sato, K.; Sugawara, K.; Takeuchi, H.; Park, H. –S.; Akiyama, T.; Koyama, T.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Heterocycles 2009, 78, 1453-1462.
2008
59) “Antibacterial novel phenolic diterpenes from the bark of Podocarpus macrophyllus D. Don,” Sato, K.; Sugawara, K.; Takeuchi, Park, H. –S.; Akiyama, T.; Koyama, T.; Aoyagi, Y.; Takeya, K.; Tsugane, T.; Shimura, S. Chem. Pharm. Bull. 2008, 56, 1691-1697.
58) “Salvileucalins B, a novel diterpenoid with an unprecedented rearranged neoclerodane skeleton from Salvia leucantha Cav.,” Aoyagi, Y.; Yamazaki, A.; Nakatsugawa, C.; Fukaya, H.; Takeya, K.; Kawauchi, S.; Izumi, H. Org. Lett. 2008, 10, 4429-4432.
57) “Fluorination of triptolide and its analogues with their cytotoxicity,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Matsuyama, S.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S. Bioorg. Med. Chem. Lett. 2008, 18, 2459-2463.
56) “Efficient synthesis of 2-mono and 2,3-disubstituted indoles via palladium-catalyzed oxidation of aminoalcohols,” Aoyagi, Y.; Shishikura, M.; Mizusaki, T.; Komine, T.; Yoshinaga, T.; Inaba, H.; Ohta, A.; Takeya, K. Heterocycles 2008, 75, 1055-1059.
2007
55) “Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG,” Villeneuve, M.; Kawai, M.; Watanabe, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnkin, D. E.; Nakahara, H. Biochim. Biophys. Acta 2007, 1768, 1717-1726.
54) “Three new diterpenoids, tricalysiolide H and tricalysiones A and B, from Tricalysia dubia," Nishimura, K.; Hitotsuyanagi, Y.; Sakakura, K.; Fujita, K.; Tachihara, S.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; Takeya, K. Tetrahedron 2007, 63, 4558-4562.
53) “Tricalysiamide A-D, diterpenpid slkaloids from Tricalysia dubia,” Nishimura, K.; Hitotsuyanagi, Y.; Sugeta, N.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; Takeya, K. J. Nat. Prod. 2007, 70, 758- 762.
2006
52) “Semisynthesis of isetexane diterpenoid analogues and their cytotoxic activity,” Aoyagi, Y.; Takahashi , Y.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.;Hashimoto, S.; Kurihara, T. Chem Pharm. Bull. 2006, 54, 1602-1604.
51) “Efficient synthesis of pyrroles and 4,5,6,7-tetrahydroindoles via palladium-catalyzed oxidation of Hydroxy-Enamines,” Aoyagi, Y.; Mizusaki, T.; Shishikura, M.; Komine, T.; Yoshinaga, T.; Inaba, H.; and Ohta, A.; Takeya, K. Tetrahedron 2006, 62, 8533-8538.
50) “Synthesis of 1-O- or 12-O-mono- and 1-O,12-O-diacylexcisanin A 7,14-acetonides and their cytotoxic activity,” Aoyagi, Y.; Nishioka, Y.; Tobe, F.; Hasuda, T.; Takeya, K.; Gui, M. –Y.; Jin, Y. –R; Li, X. –W. Bioorg. Med. Chem 2006, 14, 5802-5811.
49) “Cytotoxity of abietane diterpenoids from Perovskia abrotanoides and their semisynthetic analogues,” Aoyagi, Y.; Takahashi, Y.; Satake, Y.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S.; Kurihara, T. Bioorg. Med. Chem. 2006, 14, 5285-5291.
48) “Semisynthesis of C-ring modified triptolide analogues and their cytotoxic activities,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S. Bioorg. Med. Chem. Lett. 2006, 16, 1947-1949.
47) “Tricalysiolides A-F, new rearranged ent-kaurene diterpenes, from Tricalysia dubia,” Nishimura, K.; Hitotsuyanagi, Y.; Sugeta, N.; Sakakura, K.; Fujita, K.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; He, D. –H.; Otsuka, H.; Takeda, Y.; Takeya, K. Tetrahedron 2006, 62, 1512-1519.
2005
46) “Biomimetic synthesis of grandione from demethylsalvicanol via Hetero Diels-Alder type dimerization and structure revision of grandione,” Aoyagi, Y.; Takahashi, Y.; Satake, Y.; Fukaya, H.; Takeya, K.; Aiyama,; Matsuzaki, T.; Hashimoto, S.; Shiina, T.; Kurihara, T. Tetrahedron Lett. 2005, 46, 7885-7887.
45) “Asymmetric synthesis of (2R,3R,4R)-3-hydroxy-4-methylproline via chromium(II) chloride-mediated coupling reactions of (S)-Garner aldehyde with crotyl bromide,” Inaba, H.; Hiraiwa, Y.; Yoshida, S.; Tamura, M.; Kuroda, A.; Ogawa, A.;Aoyagi, Y.; Ohta, A.; and Takeya, K. Heterocycles 2005, 65, 2657-2665.
44) “The isolation and structure elucidation of a new sesquiterpene lactone from a poisonous plant Coriaria japonica (Coriariaceae),” Kinoshita, T.; Itaki, N.; Hikita, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K. Chem. Pharm. Bull. 2005, 53, 1040-1042.
2004
43) “New cytotoxic norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki,” Park, H. -S.; Kai, N.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Heterocycles 2004, 63, 347-357.
42) “Efficient synthesis of novel cytotoxic cis-fused alfa-methylene beta-lactones from 7,14-diihydroxy-ent-Kaurenes by transformation under Mitsunobu reaction conditions: synthsis of novel cytotoxic cis-Fused alfa-Methylene beta-lactones,” Aoyagi, Y.; Gui, M. –Y.;,Jin, Y. –R.; Li, X. –W.; Noguchi, T.; Fukaya, H.; Hasuda, T.; Takeya, K. Tetrahedron Lett. 2004, 45, 1421-1425.
41) “Rakanmakilactones A-F, new cytotoxic sulfur-containing norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki,” Park, H. –S.; Yoda, N.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Tetrahedron 2004, 60, 171-177.
40) “Excisanin H, a novel cytotoxic 14, 20-epoxy-ent-kaurene diterpenoid, and three new ent-kaurene diterpenoids from Rabdosia excisa,” Gui, M.; Aoyagi, Y.; Jin, Y.; Li, X.; Hasuda, T.; and Takeya, K. J. Nat. Prod. 2004, 67, 373-376.
2003
39) “Lipase TL®-mediated kinetic resolution of 5-benzyloxy-1-tert-butyldimethylsilyloxy-2-pentanol at low temperature: concise asymmetric synthesis of both enantiomers of a piperazic acid derivative,”Aoyagi, Y.; Saitoh, Y.; Ueno, T.; Horiguchi, M.; Takeya, K.; and Williams, R. M. J. Org. Chem. 2003, 68, 6899-6904.
38) “SR-Podolactone D, a new sulfoxide containing norditerpene dilactone from Podocarpus macrophyllus var. maki,” Park, H. –S.; Takahashi, Y.; Fukaya, H.; Aoyagi Y.; Takeya, K. J. Nat. Prod. 2003, 66, 282-284.
2002
37) “Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural princeples in mycolic acids,” Watanabe, M.; Aoyagi, Y.; Mitome, H.; Fujita, T.; Naoki, H.; Ridell, M.; Minnikin, D. E. Microbiology 2002, 148, 1881-1902.
2001
36) “Asymmetric synthesis of [2,3-13C2,15N]-4-benzyloxy-5,6-diphenyl-2,3,5,6-tetrahydro-4H-oxazine -2-one via lipase TL-mediated kinetic resolution of benzoin: general procedure for the synthesis of [2,3-13C2, 15N]-L-alanine,” Aoyagi, Y.; Iijima, A.; Williams, R. M. J. Org. Chem. 2001, 66, 8010-8014.
35) “Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, Picrotoxicin- Induced Convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain,“ Yamada, K.; Watanabe, Y; Aoyagi, Y.; Ohta, A. Biol. Pharm. Bull., 2001, 24,1068-1071.
34) “Separation and characterization of individual mycolic acids in representative mycobacteria,” Watanabe, M.; Aoyagi, Y.; Ridell, M.; Minnikin, D. E. Microbiology 2001, 147, 1825-1837.
33) “Stereocontrolled asymmetric synthesis of alfa-hydroxy-beta-amino acids. A stereodivergent approach,” Aoyagi, Y.; Jain, Rajendra P.; Williams, R. M. J. Am. Chem. Soc. 2001, 123, 3472-3477.
2000
32) “Lipase TL®-mediated kinetic resolution of benzoin: facile synthesis of (1R,2S)-erythro-2- amino-1,2-diphenylethanol,” Aoyagi, Y.; Agata, N.; Shibata, N.; Horiguchi, M.; Williams, R. M. Tetrahedron Lett. 2000, 41, 10159-10162.
31) “Pharmacological effects of urinary products obtained after treatment with saiboku-to, a herbal medicine for bronchial asthma, on type IV allergic reaction,” Taniguchi, C.; Homma M.; Takano, O.; Hirano, T.; Oka, K.; Aoyagi, Y.; Niitsuma, T.; Hayashi, T. Planta Med. 2000, 66, 607-611.
1998
30) “Chromium(II) chloride-mediated coupling reactions of Garner aldehydes with allyl bromides: facile asymmetric synthesis of (2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine," Aoyagi, Y.; Inaba, H.; Hiraiwa, Y.; Kuroda, A.; Ohta, A. J. Chem. Soc. Perkin Trans 1 1998, 3975-3978.
29) “Efficient asymmetric synthesis of (S)-2-methylasparagine,” Aoyagi, Y.; Williams, R. M. Synlett 1998, 1099-1101.
28) “Asymmetric synthesis of 1-boc-3- and 4-hydroxypyrrolidines," Aoyagi, Y.; Williams, R. M. Tetrahedron 1998, 54, 13045-13058.
27) “General asymmetric synthesis of hydroxymethylene and hydroxyethylene peptide isosteres,” Aoyagi, Y.; Williams, R. M. Tetrahedron 1998, 54, 10419-10433.
1997
26) “Anti-platelet aggregation activity of some pyrazines,” Ohta, A.; Takahashi, H.; Miyata, N.; Hirono, H.; Nishio, T.; Uchino, E.; Yamada, K.; Aoyagi, Y.; Suwabe, Y.; Fujitake, M.; Suzuki, T.; Okamoto, K. Biol. Pharm. Bull. 1997, 20, 1076-1081.
25) “Structures of phenolic glycolipids from Mycobacterium Kansasii ,” Watanabe, M.; Aoyagi, Y.; Ohta, A.; Minnikin, D. E. Eur. J. Biochem. 1997, 248, 93-98.
24) “Facile and efficient deoxygenation of aromatic N-oxides with zinc and aqueous ammonium chloride,” Aoyagi, Y.; Abe, T.; Ohta, A. Synthesis 1997, 891-894.
23) “Total synthesis of (-)-bulgecinine,” Maeda, M.; Okazaki, F.; Murayama, M.; Tachibana, Y.; Aoyagi, Y.; Ohta, A. Chem. Pharm. Bull. 1997, 45, 962-965.
1996
22) “Facile and efficient synthesis of pPyrroles and indoles via palladium-catalyzed oxidation of hydroxy-enamines and amines,” Aoyagi, Y.; Mizusaki, T.; Ohta, A. Tetrahedron Lett. 1996, 37, 9203-9206.
21) “Samarium(II) iodide-mediated iIntermolecular coupling reactions of N,N-dibenzylenamides with carbonyl compounds and transformation of the product, N,N-dibenzyl-gamma-hydroxyamide to delta-aminoalcoho ,” Aoyagi, Y.; Maeda, M.; Moro, A.; Kubota, K.; Fujii, Y.; Fukaya, H.; Ohta, A. Chem. Pharm. Bull. 1996, 44, 1812-1818.
20) “Samarium(II) iodide-mediated intermolecular coupling reactions of N,N-dibenzyl-alfa-haloamides with carbonyl compounds,” Aoyagi, Y.; Asakura, R.; Kondoh, M.; Yamamoto, R.; Kuromatsu, T.; Shimura, A.; Ohta, A. Synthesis 1996, 970-974.
19) "First total synthesis of pyrrolam A,” Aoyagi, Y.; Manabe, T.; Ohta, A.; Kurihara, T.; Pang, G. -L. Yuhara, T. Tetrahedron 1996, 52, 869-876.
1995
18) “Samariumu(II) diiodide-mediated intermolecular aldol type reactions of phenacyl bromides with carbonyl compounds,” Aoyagi, Y.; Yoshimura, M.; Tsuda, M.; Tsuchibuchi, T.; Kawamata, S.; Tateno, H.; Asano, K.; Nakamura, H.; Obokata, M.; Ohta, A.; Kodama, Y. J. Chem. Soc. Perkin Trans. 1 1995, 689-692.
17) “Synthesis of egonol and (±)-machicendiol,” Aoyagi, Y.; Mizusaki, T.; Hatori, A.; Asakura, T.; Aihara, T.; Inaba, S. Hayatsu, K.; Ohta, A. Heterocycles 1995, 41, 1077-1084.
16) “Stereoselective 1,4-dipolar cycloadditions of 2-(methylthio)-3,6-dihydro-3,5-dimethyl-6-oxo-1- substituted pyrimidine-4-olates with alkene,” Ohta, A.; Okazaki, F.; Yamanoi, Y.; Maeda, M.; Aoyagi, Y.; Kurihara, T.; Pang, G. -L. Chem. Pharm. Bull. 1995, 43, 705-707.
1994
15) “First total synthesis of (±)-oxerine,” Aoyagi, Y.; Inariyama, T.; Arai, Y.; Tsuchida, S.; Matsuda, Y.; Tateno, H.; Ohta, A. Tetrahedron 1994, 50, 13575-13582.
14) “Low-valent tantalum-mediated reaction,” Aoyagi, Y.; Tanaka, W.; Ohta, A. J. Chem. Soc., Chem. Commum. 1994, 1225-1226.
13) “First total synthesis of astechrome: novel hydroxamic acid with an indole-pyrazine skeleton,” Jing, H.; Shimada, A.; Maeda, A.; Arai, Y.; Goto, M.; Aoyagi, Y.; Ohta, A. Chem. Pharm. Bull. 1994, 42, 277- 279.
1993
12) “Approach to the synthesis of astechrome,” Jing, H.; Aoyagi, Y.; Ohta, A. Heterocycles 1993, 35, 1279-1287.
1992
11) “Synthesis of OPC-15161,” Jing, H.; Murakami, K.; Aoyagi, Y.; Ohta, A. Heterocycles 1992, 34, 1847-1856.
10) “Synthesis of 2-(indol-3-yl)mthyl-5-methylpyrazines, the skeleton of astechrome,” Ohta, A.; Jing, H.; Maeda, A.; Arai, Y.; Goto, M.; Aoyagi, Y. Heterocycles 1992, 34, 111-119.
9) “Palladium-catalyzed cross-coupling reactions of chloropyrazines with aromatic heterocycles,” Aoyagi, Y.; Inoue, A.; Koizumi, I.; Hashimoto, R.; Tokunaga, K.; Gohma, K.; Komatsu, J.; Sekine, K.; Miyafuji, A.; Kunoh, J.; Honma, R.; (the late) Akita, Y.; Ohta, A. Heterocycles 1992, 33, 257-272.
8) “Effects of the mammalian lignan 2,3-dibenzyl-butane-1,4-diol, on contraction and Ca2+ mobilization induced by noradrenaline in rat aorta,” Abe, M.; Morikawa, M.; Inoue, M.; Tsuboi, M.; Aoyagi, Y.; Ohta, A. Gen. Pharmac. 1991, 22, 663-668.
7) “Synthesis of halohydroxypyrazines and their synthetic utitility,” Aoyagi, Y.; Fujiwara, T.; Ohta, A. Heterocycles 1991, 32, 2407-2415.
6) "First synthesis of (+)-septorine,” Ohta, A.; Kojima, A.; Saito, T.; Kobayashi, K.; Saito, H; Wakabayashi, K.; Honma, S.; Sakuma, C.; Aoyagi, Y., Heterocycles 1991, 32, 923-936.
5) “Efficient alkylation and acylation of pyrazine 1-oxides,” Aoyagi, Y.; Maeda, A.;Inoue, M.; Shirahama, M.; Sakakibara, Y.; Fukui, Y.; Ohta, A. Heterocycles 1991, 32, 735-748.
1990
4) “Palladium-catalyzed arylation of furan, thiophene, benzo[b]furan, and benzo[b]thiophene,” Ohta, A.; (the late) Akita, Y.; Ohkuwa, T.; Chiba, M.; Fukunaga, R.; Miyafuji, A.; Nakata, T.; Tani, N.; Aoyagi, Y. Heterocycles 1990, 31, 1951-1958.
3) “Emeheterone: synthesis and structural revision,” Ohta, A.; Kojima, A.;
Aoyagi, Y. Heterocycles 1990, 31, 1655-1662.
1988
2) “Synthesis of argvalin and its related compound,” Ohta, A.; Aoyagi, Y.; Kurihara, T.; Kojima, A.; Yuasa, K.; Shimazaki, M., Heterocycles 1988, 27, 437-444.
1987
1) “Synthesis of arglecin ,” Ohta, A.; Aoyagi, Y.; Kurihara, T.; Yuasa, K.; Shimazaki, M. Heterocycles, 1987, 26, 3181-3191.
Review
5) “Syntheses of biologically active natural products using metal-mediated reactions as key reactions,” Aoyagi, Y. and Ohta, A. Yakugaku Zasshi 2000, 120, 1035-1050.
4) “ The chemistry ofpyrazines,” Ohta, A.; Aoyagi, Y. Reviews on Heteroatom Chem. 1998, 18, 141-167.
3) “Syntheses of naturally occurring pyrazines,” Ohta, A.; Aoyagi, Y. Yakugaku Zasshi 1997, 117, 32-48.
2) “Reactions ofpyrazines, syntheses of pyrazines,” Ohta, A.; Aoyagi, Y. Yakugaku Zasshi 1997, 117, 1-17.
1) “The chemistry of pyrazines. Syntheses of naturally occurring pyrazines,” Ohta, A.; Aoyagi, Y. Trends in Heterocyclic Chemistry, 1993, 3, 211-233.
Book
3) 薬がわかる構造式集、林 良雄,青柳 裕、飯島 洋 編、廣川書店（2013）
2) 日本薬局方要説第6版、菊川清見ら 編、廣川書店（2010).
1) CBT対策と演習「有機化学」、薬学教育研究会編、廣川書店（2008).
2018
77) "薬学部生のキャリアに対する意識調査ー女子学生が考えるキャリアとはー," 前田 徹、平松佑彩、佐伯憲一、水谷秀樹、吉川昌江、青柳 裕、矢野玲子、高橋誠弥、原崎周平、日野知証 薬学教育 2018 , 2 2018-028.
76) "Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O,20O-diacetyl kamebakaurin in mice," Yoshioka, H.; Ohnishi, H.; Yoshikawa, M.; Gui, M.-Y.; Jin, Y.-R.; Li, X.-W.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Aoyagi, Y. Fundamental Toxicol. Sci. 2018, 5, 161-165..
75) "1O,20O-diacetyl kamebakaurin protects against acetaminophen-induced hepatotoxicity in mice," Yoshioka, H.; Nonogaki, T.; Ohnishi, H.; Fukuishi, N.; Yoshikawa, M; Gui, M.-Y.; Jin, X.-R.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Aoyagi, Y. Biomed. Res. 2018, 39, 251-260.
74) "Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice," Yoshioka, H.; Mizuno, Y.; Ymamaguchi, T.; Ichimaru, Y.; Takeya, K.; Hitotsuyanagi, Y.; Nonogakl, T. Biomedicine & Pharmacotherapy 2018, 99, 214-219.
2017
73) "Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibiting lipid peroxidation and inflammatory response in mice”, Yoshioka, H.; Aoyagi, Y.; Fukuiishi, N.; Gui, M.-Y.; Jin, Y. R.; Li, X.-W.; Adachi, Y.; Ohno, N.; Takeya, K.; Hitotsuyanagi, Y.; Miura, N.; Nonogaki, T. Pharmacol. Rep. 2017, 69, 903-907.
2016
72) 図書館有効利用の一事例-金城学院大学薬学部における屋根瓦方式PBLチュートリアル教育ー,” 青柳 裕、矢野玲子、（故）安藤裕明、田中宏樹、今井和佳子、吉岡亜佳音、石田翔子、西尾十和子、今井幹典、（故）林 弥生、安田公夫、千葉 拓、日野知証 薬学図書館 2016, 61, 99-107.
2014
71) "Efficient transformation of 7,14-dihydroxy-ent-kaurenes to novel ent-abietanes having cis-fused alfa-methylene gamma-lactones under Mitsunobu reaction conditions and their cytotoxicities," Aoyagi, Y.; Ozawa, K.; Hasuda, T.; Gui, M.-Y.; Jin, Y.-R.; Li, X.-W.; Fukaya, H.; Yano, R.; Hitotsuyanagi, Y.; Takeya. K. Tetrahedron 2014, 70, 3030-3041.
70) "Semisynthesis of salvianculin E analogues and their antitrypanosomal activity," Aoyagi, Y.; Fujiwara, K.; Yamazaki, A.; Sugawara, N.; Yano, R.; Fukaya, H.; Hitotsuyanagi, Y.; Takeya, K.; Ishiyama, A.; Iwatsuki, M.; Otoguro, K.; Yamada, H.; Omura, S. Bioorg. Med. Chem. Lett. 2014, 24, 442-446.
2013
69) "Conformational folding of mycobacterial methoxy- and ketomycolic acids facilitated by alfa-methyl trans-cyclopropane groups rather than cis-cyclopropane units," Villeneuve, M.; Kawai, M.; Horiuchi, K.; Watanabe, M.; Aoyagi, Y.; Hitsotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnikin, D. E. Microbiology 2013, 159, 2405-2415.
68) "Absolute structures of stemona-lactam S and tuberostemospiroline, alkaloids from Stemona tuberosa," Fukaya, H; Hitotsuyanagi, Y.; Aoyagi, Y.; Shu, Z.; Komatsu, K.; Takeya, K. Chem. Pharm. Bull. 2013, 61, 1085-1089.
67) "Abietane diterpenoids and a seaquiterpene pyridine alkaloid from Euonymus lutchuensis," Inaba, Y.; Hasuda, T.; Hitotsuyanagi, Y.; Aoyagi, Y.; Fujikawa, N.; Onozaki, A.; Watanabe, A.; Kinoshita, T.; Takeya, K. J. Nat. Prod. 2013, 76, 1085-1090.
2011
66) “Semisynthesis of triptolide analogues part III ~ Effect of furan ring on cytotoxic activities,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Fukaya, H.; Takeya, K.;
65) “Salvilucalin C, a novel rearranged neoclerodane diterpene from Salvia leucantha,”
64) “Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-kappaB activation,” Aoyagi, Y.; Adachi, Y.; Ozawa, K.; Yokomizo, C.; Gui, M.-G.; Jin, Y.-R.; Li, Y.-R.; Ohno, N.; Takeya, K. Bioorg. Med. Chem. 2011, 19, 2450-2457.
2010
63) “Differential conformational behaviors of alfa-mycolic acids in Langmuir monolayers and computer simulations,” Villeneuve, M.; Kawai, M.; Watanabe, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnikin, D. E.; Nakahara, H. Chem. Phys. Lipids 2010, 163, 569-579.
2009
62) “First asymmetric synthesis of CJ-14877 and its enantiomer and their interleukin-1beta inhibitorty activities,” Aoyagi, Y.; Adachi, Y.; Akagi, S.; Ohno, N.; Takeya, K. Bioorg. Med. Chem. Lett. 2009, 19, 1876-1878.
61) “Cytotoxic bisnor-and norditerpene dilactones having 7alfa, 8alfa-epoxy-9,11-enolide substructure from Podocarpus macrophyllus D. Don,” Sato, K.; Inaba, Y.; Park, H. –S.; Akiyama, T.; Koyama, T.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Chem. Pharm. Bull. 2009, 57, 668-679.
60) “New cytotoxic nor- and bisnorditerpene dilactones, makilactones A-D, from Podocarpus macrophyllus D. DON,” Sato, K.; Sugawara, K.; Takeuchi, H.; Park, H. –S.; Akiyama, T.; Koyama, T.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Heterocycles 2009, 78, 1453-1462.
2008
59) “Antibacterial novel phenolic diterpenes from the bark of Podocarpus macrophyllus D. Don,” Sato, K.; Sugawara, K.; Takeuchi, Park, H. –S.; Akiyama, T.; Koyama, T.; Aoyagi, Y.; Takeya, K.; Tsugane, T.; Shimura, S. Chem. Pharm. Bull. 2008, 56, 1691-1697.
58) “Salvileucalins B, a novel diterpenoid with an unprecedented rearranged neoclerodane skeleton from Salvia leucantha Cav.,” Aoyagi, Y.; Yamazaki, A.; Nakatsugawa, C.; Fukaya, H.; Takeya, K.; Kawauchi, S.; Izumi, H. Org. Lett. 2008, 10, 4429-4432.
57) “Fluorination of triptolide and its analogues with their cytotoxicity,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Matsuyama, S.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S. Bioorg. Med. Chem. Lett. 2008, 18, 2459-2463.
56) “Efficient synthesis of 2-mono and 2,3-disubstituted indoles via palladium-catalyzed oxidation of aminoalcohols,” Aoyagi, Y.; Shishikura, M.; Mizusaki, T.; Komine, T.; Yoshinaga, T.; Inaba, H.; Ohta, A.; Takeya, K. Heterocycles 2008, 75, 1055-1059.
2007
55) “Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG,” Villeneuve, M.; Kawai, M.; Watanabe, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K.; Gouda, H.; Hirono, S.; Minnkin, D. E.; Nakahara, H. Biochim. Biophys. Acta 2007, 1768, 1717-1726.
54) “Three new diterpenoids, tricalysiolide H and tricalysiones A and B, from Tricalysia dubia," Nishimura, K.; Hitotsuyanagi, Y.; Sakakura, K.; Fujita, K.; Tachihara, S.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; Takeya, K. Tetrahedron 2007, 63, 4558-4562.
53) “Tricalysiamide A-D, diterpenpid slkaloids from Tricalysia dubia,” Nishimura, K.; Hitotsuyanagi, Y.; Sugeta, N.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; Takeya, K. J. Nat. Prod. 2007, 70, 758- 762.
2006
52) “Semisynthesis of isetexane diterpenoid analogues and their cytotoxic activity,” Aoyagi, Y.; Takahashi , Y.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.;Hashimoto, S.; Kurihara, T. Chem Pharm. Bull. 2006, 54, 1602-1604.
51) “Efficient synthesis of pyrroles and 4,5,6,7-tetrahydroindoles via palladium-catalyzed oxidation of Hydroxy-Enamines,” Aoyagi, Y.; Mizusaki, T.; Shishikura, M.; Komine, T.; Yoshinaga, T.; Inaba, H.; and Ohta, A.; Takeya, K. Tetrahedron 2006, 62, 8533-8538.
50) “Synthesis of 1-O- or 12-O-mono- and 1-O,12-O-diacylexcisanin A 7,14-acetonides and their cytotoxic activity,” Aoyagi, Y.; Nishioka, Y.; Tobe, F.; Hasuda, T.; Takeya, K.; Gui, M. –Y.; Jin, Y. –R; Li, X. –W. Bioorg. Med. Chem 2006, 14, 5802-5811.
49) “Cytotoxity of abietane diterpenoids from Perovskia abrotanoides and their semisynthetic analogues,” Aoyagi, Y.; Takahashi, Y.; Satake, Y.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S.; Kurihara, T. Bioorg. Med. Chem. 2006, 14, 5285-5291.
48) “Semisynthesis of C-ring modified triptolide analogues and their cytotoxic activities,” Aoyagi, Y.; Hitotsuyanagi, Y.; Hasuda, T.; Fukaya, H.; Takeya, K.; Aiyama, R.; Matsuzaki, T.; Hashimoto, S. Bioorg. Med. Chem. Lett. 2006, 16, 1947-1949.
47) “Tricalysiolides A-F, new rearranged ent-kaurene diterpenes, from Tricalysia dubia,” Nishimura, K.; Hitotsuyanagi, Y.; Sugeta, N.; Sakakura, K.; Fujita, K.; Fukaya, H.; Aoyagi, Y.; Hasuda, T.; Kinoshita, T.; He, D. –H.; Otsuka, H.; Takeda, Y.; Takeya, K. Tetrahedron 2006, 62, 1512-1519.
2005
46) “Biomimetic synthesis of grandione from demethylsalvicanol via Hetero Diels-Alder type dimerization and structure revision of grandione,” Aoyagi, Y.; Takahashi, Y.; Satake, Y.; Fukaya, H.; Takeya, K.; Aiyama,; Matsuzaki, T.; Hashimoto, S.; Shiina, T.; Kurihara, T. Tetrahedron Lett. 2005, 46, 7885-7887.
45) “Asymmetric synthesis of (2R,3R,4R)-3-hydroxy-4-methylproline via chromium(II) chloride-mediated coupling reactions of (S)-Garner aldehyde with crotyl bromide,” Inaba, H.; Hiraiwa, Y.; Yoshida, S.; Tamura, M.; Kuroda, A.; Ogawa, A.;Aoyagi, Y.; Ohta, A.; and Takeya, K. Heterocycles 2005, 65, 2657-2665.
44) “The isolation and structure elucidation of a new sesquiterpene lactone from a poisonous plant Coriaria japonica (Coriariaceae),” Kinoshita, T.; Itaki, N.; Hikita, M.; Aoyagi, Y.; Hitotsuyanagi, Y.; Takeya, K. Chem. Pharm. Bull. 2005, 53, 1040-1042.
2004
43) “New cytotoxic norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki,” Park, H. -S.; Kai, N.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Heterocycles 2004, 63, 347-357.
42) “Efficient synthesis of novel cytotoxic cis-fused alfa-methylene beta-lactones from 7,14-diihydroxy-ent-Kaurenes by transformation under Mitsunobu reaction conditions: synthsis of novel cytotoxic cis-Fused alfa-Methylene beta-lactones,” Aoyagi, Y.; Gui, M. –Y.;,Jin, Y. –R.; Li, X. –W.; Noguchi, T.; Fukaya, H.; Hasuda, T.; Takeya, K. Tetrahedron Lett. 2004, 45, 1421-1425.
41) “Rakanmakilactones A-F, new cytotoxic sulfur-containing norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki,” Park, H. –S.; Yoda, N.; Fukaya, H.; Aoyagi, Y.; Takeya, K. Tetrahedron 2004, 60, 171-177.
40) “Excisanin H, a novel cytotoxic 14, 20-epoxy-ent-kaurene diterpenoid, and three new ent-kaurene diterpenoids from Rabdosia excisa,” Gui, M.; Aoyagi, Y.; Jin, Y.; Li, X.; Hasuda, T.; and Takeya, K. J. Nat. Prod. 2004, 67, 373-376.
2003
39) “Lipase TL®-mediated kinetic resolution of 5-benzyloxy-1-tert-butyldimethylsilyloxy-2-pentanol at low temperature: concise asymmetric synthesis of both enantiomers of a piperazic acid derivative,”Aoyagi, Y.; Saitoh, Y.; Ueno, T.; Horiguchi, M.; Takeya, K.; and Williams, R. M. J. Org. Chem. 2003, 68, 6899-6904.
38) “SR-Podolactone D, a new sulfoxide containing norditerpene dilactone from Podocarpus macrophyllus var. maki,” Park, H. –S.; Takahashi, Y.; Fukaya, H.; Aoyagi Y.; Takeya, K. J. Nat. Prod. 2003, 66, 282-284.
2002
37) “Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural princeples in mycolic acids,” Watanabe, M.; Aoyagi, Y.; Mitome, H.; Fujita, T.; Naoki, H.; Ridell, M.; Minnikin, D. E. Microbiology 2002, 148, 1881-1902.
2001
36) “Asymmetric synthesis of [2,3-13C2,15N]-4-benzyloxy-5,6-diphenyl-2,3,5,6-tetrahydro-4H-oxazine -2-one via lipase TL-mediated kinetic resolution of benzoin: general procedure for the synthesis of [2,3-13C2, 15N]-L-alanine,” Aoyagi, Y.; Iijima, A.; Williams, R. M. J. Org. Chem. 2001, 66, 8010-8014.
35) “Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, Picrotoxicin- Induced Convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain,“ Yamada, K.; Watanabe, Y; Aoyagi, Y.; Ohta, A. Biol. Pharm. Bull., 2001, 24,1068-1071.
34) “Separation and characterization of individual mycolic acids in representative mycobacteria,” Watanabe, M.; Aoyagi, Y.; Ridell, M.; Minnikin, D. E. Microbiology 2001, 147, 1825-1837.
33) “Stereocontrolled asymmetric synthesis of alfa-hydroxy-beta-amino acids. A stereodivergent approach,” Aoyagi, Y.; Jain, Rajendra P.; Williams, R. M. J. Am. Chem. Soc. 2001, 123, 3472-3477.
2000
32) “Lipase TL®-mediated kinetic resolution of benzoin: facile synthesis of (1R,2S)-erythro-2- amino-1,2-diphenylethanol,” Aoyagi, Y.; Agata, N.; Shibata, N.; Horiguchi, M.; Williams, R. M. Tetrahedron Lett. 2000, 41, 10159-10162.
31) “Pharmacological effects of urinary products obtained after treatment with saiboku-to, a herbal medicine for bronchial asthma, on type IV allergic reaction,” Taniguchi, C.; Homma M.; Takano, O.; Hirano, T.; Oka, K.; Aoyagi, Y.; Niitsuma, T.; Hayashi, T. Planta Med. 2000, 66, 607-611.
1998
30) “Chromium(II) chloride-mediated coupling reactions of Garner aldehydes with allyl bromides: facile asymmetric synthesis of (2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine," Aoyagi, Y.; Inaba, H.; Hiraiwa, Y.; Kuroda, A.; Ohta, A. J. Chem. Soc. Perkin Trans 1 1998, 3975-3978.
29) “Efficient asymmetric synthesis of (S)-2-methylasparagine,” Aoyagi, Y.; Williams, R. M. Synlett 1998, 1099-1101.
28) “Asymmetric synthesis of 1-boc-3- and 4-hydroxypyrrolidines," Aoyagi, Y.; Williams, R. M. Tetrahedron 1998, 54, 13045-13058.
27) “General asymmetric synthesis of hydroxymethylene and hydroxyethylene peptide isosteres,” Aoyagi, Y.; Williams, R. M. Tetrahedron 1998, 54, 10419-10433.
1997
26) “Anti-platelet aggregation activity of some pyrazines,” Ohta, A.; Takahashi, H.; Miyata, N.; Hirono, H.; Nishio, T.; Uchino, E.; Yamada, K.; Aoyagi, Y.; Suwabe, Y.; Fujitake, M.; Suzuki, T.; Okamoto, K. Biol. Pharm. Bull. 1997, 20, 1076-1081.
25) “Structures of phenolic glycolipids from Mycobacterium Kansasii ,” Watanabe, M.; Aoyagi, Y.; Ohta, A.; Minnikin, D. E. Eur. J. Biochem. 1997, 248, 93-98.
24) “Facile and efficient deoxygenation of aromatic N-oxides with zinc and aqueous ammonium chloride,” Aoyagi, Y.; Abe, T.; Ohta, A. Synthesis 1997, 891-894.
23) “Total synthesis of (-)-bulgecinine,” Maeda, M.; Okazaki, F.; Murayama, M.; Tachibana, Y.; Aoyagi, Y.; Ohta, A. Chem. Pharm. Bull. 1997, 45, 962-965.
1996
22) “Facile and efficient synthesis of pPyrroles and indoles via palladium-catalyzed oxidation of hydroxy-enamines and amines,” Aoyagi, Y.; Mizusaki, T.; Ohta, A. Tetrahedron Lett. 1996, 37, 9203-9206.
21) “Samarium(II) iodide-mediated iIntermolecular coupling reactions of N,N-dibenzylenamides with carbonyl compounds and transformation of the product, N,N-dibenzyl-gamma-hydroxyamide to delta-aminoalcoho ,” Aoyagi, Y.; Maeda, M.; Moro, A.; Kubota, K.; Fujii, Y.; Fukaya, H.; Ohta, A. Chem. Pharm. Bull. 1996, 44, 1812-1818.
20) “Samarium(II) iodide-mediated intermolecular coupling reactions of N,N-dibenzyl-alfa-haloamides with carbonyl compounds,” Aoyagi, Y.; Asakura, R.; Kondoh, M.; Yamamoto, R.; Kuromatsu, T.; Shimura, A.; Ohta, A. Synthesis 1996, 970-974.
19) "First total synthesis of pyrrolam A,” Aoyagi, Y.; Manabe, T.; Ohta, A.; Kurihara, T.; Pang, G. -L. Yuhara, T. Tetrahedron 1996, 52, 869-876.
1995
18) “Samariumu(II) diiodide-mediated intermolecular aldol type reactions of phenacyl bromides with carbonyl compounds,” Aoyagi, Y.; Yoshimura, M.; Tsuda, M.; Tsuchibuchi, T.; Kawamata, S.; Tateno, H.; Asano, K.; Nakamura, H.; Obokata, M.; Ohta, A.; Kodama, Y. J. Chem. Soc. Perkin Trans. 1 1995, 689-692.
17) “Synthesis of egonol and (±)-machicendiol,” Aoyagi, Y.; Mizusaki, T.; Hatori, A.; Asakura, T.; Aihara, T.; Inaba, S. Hayatsu, K.; Ohta, A. Heterocycles 1995, 41, 1077-1084.
16) “Stereoselective 1,4-dipolar cycloadditions of 2-(methylthio)-3,6-dihydro-3,5-dimethyl-6-oxo-1- substituted pyrimidine-4-olates with alkene,” Ohta, A.; Okazaki, F.; Yamanoi, Y.; Maeda, M.; Aoyagi, Y.; Kurihara, T.; Pang, G. -L. Chem. Pharm. Bull. 1995, 43, 705-707.
1994
15) “First total synthesis of (±)-oxerine,” Aoyagi, Y.; Inariyama, T.; Arai, Y.; Tsuchida, S.; Matsuda, Y.; Tateno, H.; Ohta, A. Tetrahedron 1994, 50, 13575-13582.
14) “Low-valent tantalum-mediated reaction,” Aoyagi, Y.; Tanaka, W.; Ohta, A. J. Chem. Soc., Chem. Commum. 1994, 1225-1226.
13) “First total synthesis of astechrome: novel hydroxamic acid with an indole-pyrazine skeleton,” Jing, H.; Shimada, A.; Maeda, A.; Arai, Y.; Goto, M.; Aoyagi, Y.; Ohta, A. Chem. Pharm. Bull. 1994, 42, 277- 279.
1993
12) “Approach to the synthesis of astechrome,” Jing, H.; Aoyagi, Y.; Ohta, A. Heterocycles 1993, 35, 1279-1287.
1992
11) “Synthesis of OPC-15161,” Jing, H.; Murakami, K.; Aoyagi, Y.; Ohta, A. Heterocycles 1992, 34, 1847-1856.
10) “Synthesis of 2-(indol-3-yl)mthyl-5-methylpyrazines, the skeleton of astechrome,” Ohta, A.; Jing, H.; Maeda, A.; Arai, Y.; Goto, M.; Aoyagi, Y. Heterocycles 1992, 34, 111-119.
9) “Palladium-catalyzed cross-coupling reactions of chloropyrazines with aromatic heterocycles,” Aoyagi, Y.; Inoue, A.; Koizumi, I.; Hashimoto, R.; Tokunaga, K.; Gohma, K.; Komatsu, J.; Sekine, K.; Miyafuji, A.; Kunoh, J.; Honma, R.; (the late) Akita, Y.; Ohta, A. Heterocycles 1992, 33, 257-272.
8) “Effects of the mammalian lignan 2,3-dibenzyl-butane-1,4-diol, on contraction and Ca2+ mobilization induced by noradrenaline in rat aorta,” Abe, M.; Morikawa, M.; Inoue, M.; Tsuboi, M.; Aoyagi, Y.; Ohta, A. Gen. Pharmac. 1991, 22, 663-668.
7) “Synthesis of halohydroxypyrazines and their synthetic utitility,” Aoyagi, Y.; Fujiwara, T.; Ohta, A. Heterocycles 1991, 32, 2407-2415.
6) "First synthesis of (+)-septorine,” Ohta, A.; Kojima, A.; Saito, T.; Kobayashi, K.; Saito, H; Wakabayashi, K.; Honma, S.; Sakuma, C.; Aoyagi, Y., Heterocycles 1991, 32, 923-936.
5) “Efficient alkylation and acylation of pyrazine 1-oxides,” Aoyagi, Y.; Maeda, A.;Inoue, M.; Shirahama, M.; Sakakibara, Y.; Fukui, Y.; Ohta, A. Heterocycles 1991, 32, 735-748.
1990
4) “Palladium-catalyzed arylation of furan, thiophene, benzo[b]furan, and benzo[b]thiophene,” Ohta, A.; (the late) Akita, Y.; Ohkuwa, T.; Chiba, M.; Fukunaga, R.; Miyafuji, A.; Nakata, T.; Tani, N.; Aoyagi, Y. Heterocycles 1990, 31, 1951-1958.
3) “Emeheterone: synthesis and structural revision,” Ohta, A.; Kojima, A.;
Aoyagi, Y. Heterocycles 1990, 31, 1655-1662.
1988
2) “Synthesis of argvalin and its related compound,” Ohta, A.; Aoyagi, Y.; Kurihara, T.; Kojima, A.; Yuasa, K.; Shimazaki, M., Heterocycles 1988, 27, 437-444.
1987
1) “Synthesis of arglecin ,” Ohta, A.; Aoyagi, Y.; Kurihara, T.; Yuasa, K.; Shimazaki, M. Heterocycles, 1987, 26, 3181-3191.
Review
5) “Syntheses of biologically active natural products using metal-mediated reactions as key reactions,” Aoyagi, Y. and Ohta, A. Yakugaku Zasshi 2000, 120, 1035-1050.
4) “ The chemistry ofpyrazines,” Ohta, A.; Aoyagi, Y. Reviews on Heteroatom Chem. 1998, 18, 141-167.
3) “Syntheses of naturally occurring pyrazines,” Ohta, A.; Aoyagi, Y. Yakugaku Zasshi 1997, 117, 32-48.
2) “Reactions ofpyrazines, syntheses of pyrazines,” Ohta, A.; Aoyagi, Y. Yakugaku Zasshi 1997, 117, 1-17.
1) “The chemistry of pyrazines. Syntheses of naturally occurring pyrazines,” Ohta, A.; Aoyagi, Y. Trends in Heterocyclic Chemistry, 1993, 3, 211-233.
Book
3) 薬がわかる構造式集、林 良雄,青柳 裕、飯島 洋 編、廣川書店（2013）
2) 日本薬局方要説第6版、菊川清見ら 編、廣川書店（2010).
1) CBT対策と演習「有機化学」、薬学教育研究会編、廣川書店（2008).